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Is Paget's disease inherited? Doctors are not sure what causes the disease. Some people have hereditary Paget's disease, which means it runs in their family and was passed down by their parents. But most people do not have any relatives with Paget's disease. Doctors think a virus may cause Paget's disease in some cases.
How is Paget's disease caused? The cause of Paget's disease of bone is unknown. Scientists suspect a combination of environmental and genetic factors contribute to the disease. Some scientists believe Paget's disease of bone is related to a viral infection in your bone cells, but this theory is controversial.
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